集萃药康|BALB/c-hPD1

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BALB/cJGpt-Pdcd1^{em1Cin(hPDCD1)}/ Gpt

BALB/c-hPD1|Strain NO.T002726

Knockin(KI)

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BALB/cJGpt-Pdcd1^{em1Cin(hPDCD1)}/ Gpt

BALB/c-hPD1|Strain NO.T002726

Knockin(KI)

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BALB/cJGpt-Pdcd1^{em1Cin(hPDCD1)}/ Gpt

BALB/c-hPD1|Strain NO.T002726

Knockin(KI)

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BALB/cJGpt-Pdcd1^{em1Cin(hPDCD1)}/ Gpt

BALB/c-hPD1|Strain NO.T002726

Knockin(KI)

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基本信息

基因官方名：Pdcd1,PDCD1
基因全名：programmed cell death 1
基因别名：PD-1,Pdc1,Ly101,PD1,PD-1,CD279,SLEB2,hPD-1,hPD-l,hSLE1
NCBI：18566#5133
MGI：104879

销售状态：IF(正常销售)
保存方式： 活体,冷冻
品系背景：[N000020] BALB/cJGpt
微生物等级： SPF级

品系策略： 登录后查看品系策略，点我登录
品系策略： T002726.BALBc-hPD1 品系资料.pdf T002726.BALBc-hPD1 strain info.pdf
研究领域：人源化模型,基因人源化模型
领域描述：1.人类PD1抑制剂药效评价如：筛选人类PD1中和性抗体或抑制人类PD1活性的小分子药物;2.抗人PD1抗体安全性评价3.免疫系统相关研究。

发表文献：

Oncolytic virus expressing PD-1 inhibitors activates a collaborative intratumoral immune response to control tumor and synergizes with CTLA-4 or TIM-3 blockade https://doi.org/10.1136/jitc-2022-004762

Fc-Fc interactions and immune inhibitory effects of IgG4: implications for anti-PD-1 immunotherapies https://doi.org/10.1136/jitc-2024-009034

*使用本品系发表的文献需注明：BALB/c-hPD1 mice（Strain NO.T002726）were purchased from GemPharmatech (Nanjing, China).

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