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C57BL/6JGpt-Apcem1Cin(Min)/Gpt
APC-min|Strain
NO.T001457
Point mutation (PM)
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C57BL/6JGpt-Apcem1Cin(Min)/Gpt
APC-min|Strain
NO.T001457
Point mutation (PM)
- 性别： --
- 周龄： --
- 基因型： --
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C57BL/6JGpt-Apcem1Cin(Min)/Gpt
APC-min|Strain
NO.T001457
Point mutation (PM)
性 别
周 龄
基因型
*以发货时库存基因型为准
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- 基本信息
- 销售状态：IF(正常销售)
- 保存方式： 活体,冷冻
- 品系背景：[N000013] C57BL/6JGpt
- 微生物等级： SPF级
- 品系策略： 登录后查看品系策略，点我登录
- 品系策略： T001457.Apc-min strain info.pdf T001457.Apc-min 品系资料.pdf
- 研究领域：疾病与药物评价模型,肿瘤模型
- 领域描述：1.癌症研究(消化道肿瘤.腺瘤);2.抗肠道肿瘤小分子药物筛选。
- 发表文献：
Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors https://doi.org/10.1038/s41467-020-15729-4 Probiotic strain Lactobacillus plantarum YYC-3 prevents colon cancer in mice by regulating the tumour microenvironment https://doi.org/10.1016/j.biopha.2020.110159 Gambogenic acid induces Noxa-mediated apoptosis in colorectal cancer through ROS-dependent activation of IRE1α/JNK https://doi.org/10.1016/j.phymed.2020.153306 Anti-colon cancer activity of water-soluble polysaccharides extracted from Gloeostereum incarnatum via Wnt/β-catenin signaling pathway https://doi.org/10.1016/j.fshw.2021.04.008 The protection of crocin against ulcerative colitis and colorectal cancer via suppression of NF-κB-mediated inflammation https://doi.org/10.3389/fphar.2021.639458 Effect of pristimerin on apoptosis through activation of ROS/endoplasmic reticulum (ER) stress-mediated noxa in colorectal cancer https://doi.org/10.1016/j.phymed.2020.153399 ZhenQi FuZheng formula inhibits the growth of colorectal tumors by modulating intestinal microflora-mediated immune function PMC9217701 Calf Thymus Polypeptide Restrains the Growth of Colorectal Tumor via Regulating the Intestinal Microbiota-Mediated Immune Function https://doi.org/10.3389/fphar.2022.898906 IL-36γ and IL-36Ra Reciprocally Regulate Colon Inflammation and Tumorigenesis by Modulating the Cell-Matrix Adhesion Network and Wnt Signaling https://doi.org/10.1002/advs.202103035 p53 promotes peroxisomal fatty acid beta-oxidation to repress purine biosynthesis and mediate tumor suppression https://doi.org/10.1038/s41419-023-05625-2 Overdose intake of Neu5Gc triggers colorectal inflammation and alters liver metabolism https://doi.org/10.1080/09540105.2023.2281274 A novel antidiuretic hormone governs tumour-induced renal dysfunction https://doi.org/10.1038/s41586-023-06833-8 A multiomics analysis-assisted deep learning model identifies a macrophage-oriented module as a potential therapeutic target in colorectal cancer https://doi.org/10.1016/j.xcrm.2024.101399 A Free Amino Acid Diet Alleviates Colorectal Tumorigenesis through Modulating Gut Microbiota and Metabolites https://doi.org/10.3390/nu16071040 Exposure to Microcystin-LR Promotes Colorectal Cancer Progression by Altering Gut Microbiota and Associated Metabolites in APC(min/+) Mice https://doi.org/10.3390/toxins16050212 Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/− mice https://doi.org/10.1016/j.isci.2024.110205 BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism https://doi.org/10.1016/j.chom.2024.07.012 CDKL3 is a targetable regulator of cell cycle progression in cancers https://doi.org/10.1172/JCI178428 Astragaloside IV Ameliorates Colonic Adenomatous Polyps Development by Orchestrating Gut Bifidobacterium and Serum Metabolome https://doi.org/10.1142/S0192415X24500605 Dysbiosis promotes recurrence of adenomatous polyps in the distal colorectum https://doi.org/10.4251/wjgo.v16.i8.3600
*使用本品系发表的文献需注明：APC-min mice（Strain NO.T001457）were purchased from GemPharmatech (Nanjing, China).
