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C57BL/6JGpt
C57BL/6JGpt|Strain
NO.N000013
Inbred strain
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- 基因型： --
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C57BL/6JGpt
C57BL/6JGpt|Strain
NO.N000013
Inbred strain
性 别
周 龄
基因型
*以发货时库存基因型为准
小鼠分类
- 选择数量：
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- 基本信息
- NCBI：暂无
- 销售状态：IF(正常销售)
- 保存方式： 活体,冷冻
- 品系背景：[N000013] C57BL/6JGpt
- 微生物等级： SPF级
- 品系策略： 登录后查看品系策略，点我登录
- 品系策略： N000013.C57BL_6JGpt strain info.pdf N000013.C57BL_6JGpt 品系资料.pdf
- 领域描述：1.糖饮食诱导的动脉粥样硬化2.淋巴组织缺陷3.高血糖症代谢研究4.造血缺陷5.听力缺陷。
- 发表文献：
Antifibrotic Effects of Tetrahedral Framework Nucleic Acids by Inhibiting Macrophage Polarization and Macrophage-Myofibroblast Transition in Bladder Remodeling https://doi.org/10.1002/adhm.202203076 Natural Cell Patches: Melanin Nanoparticles for MR Imaging‐Guided Antiatherosclerosis Therapy via Attenuating Macrophage Pyroptosis https://doi.org/10.1002/adfm.202212748 Construction of a cross-species cell landscape at single-cell level https://doi.org/10.1093/nar/gkac633 A nanomaterial targeting the spike protein captures SARS-CoV-2 variants and promotes viral elimination https://doi.org/10.1038/s41565-022-01177-2 Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4 https://doi.org/10.1126/sciadv.abo0340 ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia https://doi.org/10.1038/s41423-022-00881-2 Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver https://doi.org/10.1016/j.cellimm.2022.104575 Pirfenidone attenuates cardiac hypertrophy against isoproterenol by inhibiting activation of the janus tyrosine kinase-2/signal transducer and activator of transcription 3 (JAK-2/STAT3) signaling pathway https://doi.org/10.1080/21655979.2022.2073145 Dendrocalamus latiflorus and its component rutin exhibit glucose-lowering activities by inhibiting hepatic glucose production via AKT activation https://doi.org/10.1016/j.apsb.2021.11.017 Glucose-sensing glucagon-like peptide-1 receptor neurons in the dorsomedial hypothalamus regulate glucose metabolism https://doi.org/10.1126/sciadv.abn5345 IL‐36γ and IL‐36Ra Reciprocally Regulate NSCLC Progression by Modulating GSH Homeostasis and Oxidative Stress‐Induced Cell Death https://doi.org/10.1002/advs.202101501 Hypoglycemic and hypolipidemic effects of blueberry anthocyanins by AMPK activation: In vitro and in vivo studies https://doi.org/10.1016/j.redox.2021.102100 Allosteric inhibition reveals SHP2-mediated tumor immunosuppression in colon cancer by single-cell transcriptomics https://doi.org/10.1016/j.apsb.2021.08.006 Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice https://doi.org/10.1016/j.apsb.2020.12.008 ATM/NEMO signaling modulates the expression of PD-L1 following docetaxel chemotherapy in prostate cancer http://dx.doi.org/10.1136/jitc-2020-001758 GPR43 deficiency protects against podocyte insulin resistance in diabetic nephropathy through the restoration of AMPKα activity https://www.thno.org/v11p4728.htm MicroRNA-146a switches microglial phenotypes to resist the pathological processes and cognitive degradation of Alzheimer's disease https://www.thno.org/v11p4103.htm Blockade of checkpoint receptor PVRIG unleashes anti-tumor immunity of NK cells in murine and human solid tumors https://doi.org/10.1186/s13045-021-01112-3 Targeting regulator of G protein signaling 1 in tumor-specific T cells enhances their trafficking to breast cancer https://doi.org/10.1038/s41590-021-00939-9 Smart Acid‐Activatable Self‐Assembly of Black Phosphorous as Photosensitizer to Overcome Poor Tumor Retention in Photothermal Therapy https://doi.org/10.1002/adfm.202003338 PARP14 inhibits microglial activation via LPAR5 to promote post-stroke functional recovery https://doi.org/10.1080/15548627.2020.1847799 Selection of a Full Agonist Combinatorial Antibody that Rescues Leptin Deficiency In Vivo https://doi.org/10.1002/advs.202000818 The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity https://doi.org/10.1016/j.cmet.2021.02.007 N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression https://doi.org/10.1016/j.molcel.2021.07.003 Endothelial caveolin-1 regulates cerebral thrombo-inflammation in acute ischemia/reperfusion injury http://doi.org/10.1016/j.ebiom.2022.104275 CD11b(+) CD43(hi) Ly6C(lo) splenocyte-derived macrophages exacerbate liver fibrosis via spleen-liver axis http://doi.org/10.1002/hep.32782 Regulation of Podocyte Injury by CircHIPK3/FUS Complex in Diabetic Kidney Disease http://doi.org/10.7150/ijbs.75994 MAP7D2 reduces CD8(+) cytotoxic T lymphocyte infiltration through MYH9-HMGB1 axis in colorectal cancer http://doi.org/10.1016/j.ymthe.2022.09.001 Advanced glycation end products induce senescence of atrial myocytes and increase susceptibility of atrial fibrillation in diabetic mice http://doi.org/10.1111/acel.13734 The m(6)A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia http://doi.org/10.1016/j.ccell.2022.10.004 α-D-1,3-glucan from Radix Puerariae thomsonii improves NAFLD by regulating the intestinal flora and metabolites http://doi.org/10.1016/j.carbpol.2022.120197 Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming http://doi.org/10.1038/s41421-022-00447-6 Circular RNA CREBBP modulates cartilage degradation by activating the Smad1/5 pathway through the TGFβ2/ALK1 axis http://doi.org/10.1038/s12276-022-00865-2 TDO2+ myofibroblasts mediate immune suppression in malignant transformation of squamous cell carcinoma http://doi.org/10.1172/JCI157649 Targeting cathepsin B by cycloastragenol enhances antitumor immunity of CD8 T cells via inhibiting MHC-I degradation http://doi.org/10.1136/jitc-2022-004874 Atmospheric particulate matter impairs cognition by modulating synaptic function via the nose-to-brain route http://doi.org/10.1016/j.scitotenv.2022.159600 Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor https://doi.org/10.1038/s41467-022-34692-w Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment https://doi.org/10.1038/s41467-022-34495-z Vascular endothelium deploys caveolin-1 to regulate oligodendrogenesis after chronic cerebral ischemia in mice https://doi.org/10.1038/s41467-022-34293-7 Long-term cadmium exposure impairs cognitive function by activating lnc-Gm10532/m6A/FIS1 axis-mediated mitochondrial fission and dysfunction https://doi.org/10.1016/j.scitotenv.2022.159950 Single-cell RNA sequencing combined with single-cell proteomics identifies the metabolic adaptation of islet cell subpopulations to high-fat diet in mice https://doi.org/10.1007/s00125-022-05849-5 The Transient Receptor Potential Vanilloid 2 (TRPV2) Channel Facilitates Virus Infection Through the Ca(2+) -LRMDA Axis in Myeloid Cells https://doi.org/10.1002/advs.202202857 Use of intercellular proximity labeling to quantify and decipher cell-cell interactions directed by diversified molecular pairs https://doi.org/10.1126/sciadv.add2337 Macrophage GSK3beta-deficiency inhibits the progression of hepatocellular carcinoma and enhances the sensitivity of anti-PD1 immunotherapy https://doi.org/10.1136/jitc-2022-005655 Circular RNA CREBBP modulates cartilage degradation by activating the Smad1/5 pathway through the TGFbeta2/ALK1 axis https://doi.org/10.1038/s12276-022-00865-2 FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury https://doi.org/10.1038/s41392-022-01254-x Positive feedback loop of miR-320 and CD36 regulates the hyperglycemic memory-induced diabetic diastolic cardiac dysfunction https://doi.org/10.1016/j.omtn.2022.12.009 Prodrug Integrated Envelope on Probiotics to Enhance Target Therapy for Ulcerative Colitis https://doi.org/10.1002/advs.202205422 Single-cell transcriptomic dissection of the cellular and molecular events underlying the triclosan-induced liver fibrosis in mice https://doi.org/10.1186/s40779-023-00441-3 FTO-dependent m(6)A modification of Plpp3 in circSCMH1-regulated vascular repair and functional recovery following stroke https://doi.org/10.1038/s41467-023-36008-y Unique DUOX2(+)ACE2(+) small cholangiocytes are pathogenic targets for primary biliary cholangitis https://doi.org/10.1038/s41467-022-34606-w Dimethyl fumarate inhibits necroptosis and alleviates systemic inflammatory response syndrome by blocking the RIPK1-RIPK3-MLKL axis https://doi.org/10.1016/j.phrs.2023.106697 Neuron stem cell NLRP6 sustains hippocampal neurogenesis to resist stress-induced depression https://doi.org/10.1016/j.apsb.2023.03.010 G protein-coupled receptor 35 attenuates nonalcoholic steatohepatitis by reprogramming cholesterol homeostasis in hepatocytes https://doi.org/10.1016/j.apsb.2022.10.011 Costunolide covalently targets NACHT domain of NLRP3 to inhibit inflammasome activation and alleviate NLRP3-driven inflammatory diseases https://doi.org/10.1016/j.apsb.2022.09.014 miR-204 ameliorates osteoarthritis pain by inhibiting SP1-LRP1 signaling and blocking neuro-cartilage interaction https://doi.org/10.1016/j.bioactmat.2023.03.010 Macrophage DCLK1 promotes atherosclerosis via binding to IKKbeta and inducing inflammatory responses https://doi.org/10.15252/emmm.202217198 PD-L1 promotes GSDMD-mediated NET release by maintaining the transcriptional activity of Stat3 in sepsis-associated encephalopathy https://doi.org/10.7150/ijbs.79913 PES1 reduces CD8(+) T cell infiltration and immunotherapy sensitivity via interrupting ILF3-IL15 complex in esophageal squamous cell carcinoma https://doi.org/10.1186/s12929-023-00912-8 Bioabsorbable nano-micelle hybridized hydrogel scaffold prevents postoperative melanoma recurrence https://doi.org/10.1016/j.jconrel.2023.03.005 BRD9-mediated chromatin remodeling suppresses osteoclastogenesis through negative feedback mechanism https://doi.org/10.1038/s41467-023-37116-5 Lipid-accumulated reactive astrocytes promote disease progression in epilepsy https://doi.org/10.1038/s41593-023-01288-6 Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer https://doi.org/10.1007/s12015-023-10518-0 Myeloid-specific blockade of Notch signaling ameliorates nonalcoholic fatty liver disease in mice https://doi.org/10.7150/ijbs.80122 Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice https://doi.org/10.1038/s41467-023-37459-z Single-cell analyses reveal cannabidiol rewires tumor microenvironment via inhibiting alternative activation of macrophage and synergizes with anti-PD-1 in colon cancer https://doi.org/10.1016/j.jpha.2023.04.013 The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway https://doi.org/10.1038/s41536-023-00294-3 Upregulation of beta-catenin signaling represents a single common pathway leading to the various phenotypes of spinal degeneration and pain https://doi.org/10.1038/s41413-023-00253-0 Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury https://doi.org/10.1002/advs.202206606 C-C motif chemokine receptor 2 inhibition reduces liver fibrosis by restoring the immune cell landscape https://doi.org/10.7150/ijbs.83530 Design of a novel chimeric peptide via dual blockade of CD47/SIRPalpha and PD-1/PD-L1 for cancer immunotherapy https://doi.org/10.1007/s11427-022-2285-6 Dysregulated Gln-Glu-alpha-ketoglutarate axis impairs maternal decidualization and increases the risk of recurrent spontaneous miscarriage https://doi.org/10.1016/j.xcrm.2023.101026 Infusion of GMSCs relieves autoimmune arthritis by suppressing the externalization of neutrophil extracellular traps via PGE2-PKA-ERK axis https://doi.org/10.1016/j.jare.2023.05.001 Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury https://doi.org/10.1002/advs.202205436 beta-Nicotinamide mononucleotide activates NAD+/SIRT1 pathway and attenuates inflammatory and oxidative responses in the hippocampus regions of septic mice https://doi.org/10.1016/j.redox.2023.102745 B4GALT1 promotes immune escape by regulating the expression of PD-L1 at multiple levels in lung adenocarcinoma https://doi.org/10.1186/s13046-023-02711-3 Bmal1 downregulation leads to diabetic cardiomyopathy by promoting Bcl2/IP3R-mediated mitochondrial Ca(2+) overload https://doi.org/10.1016/j.redox.2023.102788 Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice https://doi.org/10.1186/s12929-023-00933-3 Irisin inhibits neutrophil extracellular traps formation and protects against acute pancreatitis in mice https://doi.org/10.1016/j.redox.2023.102787 Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes https://doi.org/10.1038/s41556-023-01155-3 The Combination of R848 with Sorafenib Enhances Antitumor Effects by Reprogramming the Tumor Immune Microenvironment and Facilitating Vascular Normalization in Hepatocellular Carcinoma https://doi.org/10.1002/advs.202207650 Zoledronic acid and thymosin alpha1 elicit antitumor immunity against prostate cancer by enhancing tumor inflammation and cytotoxic T cells https://doi.org/10.1136/jitc-2022-006381 Low‐intensity pulsed ultrasound alleviates doxorubicin‐induced cardiotoxicity via inhibition of S100a8/a9‐mediated cardiac recruitment of neutrophils https://doi.org/10.1002/btm2.10570 Purinergic receptor P2Y12 boosts autoimmune hepatitis through hexokinase 2-dependent glycolysis in T cells https://doi.org/10.7150/ijbs.85133 Skeletal muscle-specific DJ-1 ablation-induced atrogenes expression and mitochondrial dysfunction contributing to muscular atrophy https://doi.org/10.1002/jcsm.13290 Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing https://doi.org/10.1016/j.xcrm.2023.101129 The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice https://doi.org/10.1038/s41467-023-39710-z Chronic stress accelerates glioblastoma progression via DRD2/ERK/beta-catenin axis and Dopamine/ERK/TH positive feedback loop https://doi.org/10.1186/s13046-023-02728-8 Flavonoid Derivative DMXAA Attenuates Cisplatin-induced Acute Kidney Injury Independent of STING Signaling https://doi.org/10.1042/CS20220728 Vimentin affects inflammation and neutrophil recruitment in airway epithelium during Streptococcus suis serotype 2 infection https://doi.org/10.1186/s13567-023-01135-3 Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke https://doi.org/10.1016/j.celrep.2023.112233 Reduced Vrk2 expression is associated with higher risk of depression in humans and mediates depressive-like behaviors in mice https://doi.org/10.1186/s12916-023-02945-0 RNAi targeting heparin cofactor II promotes hemostasis in hemophilia A https://doi.org/10.1016/j.omtn.2021.03.022 Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis https://doi.org/10.1038/s41420-023-01546-3 Bile acid-dependent transcription factors and chromatin accessibility determine regional heterogeneity of intestinal antimicrobial peptides https://doi.org/10.1038/s41467-023-40565-7 Cholesterol removal improves performance of a model biomimetic system to co-deliver a photothermal agent and a STING agonist for cancer immunotherapy https://doi.org/10.1038/s41467-023-40814-9 Combination of bacterial-targeted delivery of gold-based AIEgen radiosensitizer for fluorescence-image-guided enhanced radio-immunotherapy against advanced cancer https://doi.org/10.1016/j.bioactmat.2023.05.010 Development and Validation of Robust Ferroptosis-Related Genes in Myocardial Ischemia-Reperfusion Injury https://doi.org/10.3390/jcdd10080344 Intravesical chemotherapy synergize with an immune adjuvant by a thermo-sensitive hydrogel system for bladder cancer https://doi.org/10.1016/j.bioactmat.2023.08.013 Licochalcone B confers protective effects against LPS-Induced acute lung injury in cells and mice through the Keap1/Nrf2 pathway https://doi.org/10.1080/13510002.2023.2243423 Microglia sense and suppress epileptic neuronal hyperexcitability https://doi.org/10.1016/j.phrs.2023.106881 Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast https://doi.org/10.1016/j.ijrobp.2023.07.033 Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization https://doi.org/10.1038/s41598-023-40404-1 PAX5 and circ1857 affected DLBCL progression and B-cell proliferation through regulating GINS1 https://doi.org/10.1111/cas.15856 Pomegranate-derived exosome-like nanovesicles ameliorate high-fat diet-induced nonalcoholic fatty liver disease via alleviating mitochondrial dysfunction https://doi.org/10.1016/j.jff.2023.105734 PPARalpha/ACOX1 as a novel target for hepatic lipid metabolism disorders induced by per- and polyfluoroalkyl substances: An integrated approach https://doi.org/10.1016/j.envint.2023.108138 Sandwich-Structured Implants to Obstruct Multipath Energy Supply and Trigger Self-Enhanced Hypoxia-Initiated Chemotherapy Against Postsurgical Tumor Recurrence and Metastasis https://doi.org/10.1002/advs.202300899 Multi-omics reveals aspirin eugenol ester alleviates neurological disease https://doi.org/10.1016/j.biopha.2023.115311 Thioredoxin-1 promotes the restoration of alveolar bone in periodontitis with diabetes https://doi.org/10.1016/j.isci.2023.107618 C3aR contributes to unilateral ureteral obstruction-induced renal interstitial fibrosis via the activation of the NLRP3 inflammasome https://doi.org/10.1016/j.lfs.2022.120905 Antigen priming induces functional reprogramming in iNKT cells via metabolic and epigenetic regulation An insight into iNKT cell-based anti-tumor immunotherapy https://doi.org/10.1158/2326-6066.CIR-23-0448 Characterisation of forkhead box protein A3 as a key transcription factor for hepatocyte regeneration https://doi.org/10.1016/j.jhepr.2023.100906 DOCK8 inhibits the immune function of neutrophils in sepsis by regulating aerobic glycolysis https://doi.org/10.1002/iid3.965 Enhanced systemic tumor suppression by in situ vaccine combining radiation and OX40 agonist with CpG therapy https://doi.org/10.1186/s12967-023-04504-w Enteric fungi protect against intestinal ischemia-reperfusion injury via inhibiting the SAA1-GSDMD pathway https://doi.org/10.1016/j.jare.2023.09.008 HIVEP3 inhibits fate decision of CD8+ invariant NKT cells after positive selection https://doi.org/10.1093/jleuko/qiad082 Hyperglycemia-induced myocardial fibrosis may be associated with pyroptosis and apoptosis of cardiomyoctes in diabetic mice https://doi.org/10.32604/biocell.2023.024944 Identification and analysis of key genes in adipose tissue for human obesity based on bioinformatics https://doi.org/10.1016/j.gene.2023.147755 J147 ameliorates sepsis-induced depressive-like behaviors in mice by attenuating neuroinflammation through regulating the TLR4/NF-kappaB signaling pathway https://doi.org/10.1007/s10735-023-10147-4 Multifunctional nanozyme-reinforced copper-coordination polymer nanoparticles for drug-resistance bacteria extinction and diabetic wound healing https://doi.org/10.1186/s40824-023-00429-z Neuregulin4 Acts on Hypothalamic ErBb4 to Excite Oxytocin Neurons and Preserve Metabolic Homeostasis https://doi.org/10.1002/advs.202204824 Oit3, a promising hallmark gene for targeting liver sinusoidal endothelial cells https://doi.org/10.1038/s41392-023-01621-2 PC3T: a signature-driven predictor of chemical compounds for cellular transition https://doi.org/10.1038/s42003-023-05225-y Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate https://doi.org/10.1016/j.xpro.2023.102554 Suppressive stroma-immune prognostic signature impedes immunotherapy in ovarian cancer and can be reversed by PDGFRB inhibitors https://doi.org/10.1186/s12967-023-04422-x Triptolide attenuates pulmonary fibrosis by inhibiting fibrotic extracellular matrix remodeling mediated by MMPs/LOX/integrin https://doi.org/10.1016/j.biopha.2023.115394 Cancer cells reprogram to metastatic state through the acquisition of platelet mitochondria https://doi.org/10.1016/j.celrep.2023.113147 The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages https://doi.org/10.1038/s41419-022-05115-x The perinuclear theca protein Calicin helps shape the sperm head and maintain the nuclear structure in mice https://doi.org/10.1016/j.celrep.2022.111049 Actin polymerization inhibition by targeting ARPC2 affects intestinal stem cell homeostasis https://doi.org/10.1093/burnst/tkad038 Astragaloside IV Ameliorates Inflammatory Damage in Mice with Acute Liver Failure https://doi.org/10.4236/cm.2023.144011 Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling https://doi.org/10.1038/s41467-023-42179-5 CircRNA itchy E3 ubiquitin protein ligase improves mitochondrial dysfunction in sepsis-induced acute kidney injury by targeting microRNA-214-3p/ATP-binding cassette A1 axis https://doi.org/10.1080/0886022X.2023.2261552 Development of cyclopeptide inhibitors of cGAS targeting protein-DNA interaction and phase separation https://doi.org/10.1038/s41467-023-41892-5 Dexmedetomidine Ameliorates Cardiac Ischemia/Reperfusion Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT3 Pathway https://doi.org/10.2147/DDDT.S428024 Dopaminergic neurodegeneration in the substantia nigra is associated with olfactory dysfunction in mice models of Parkinson's disease https://doi.org/10.1038/s41420-023-01684-8 Engineered oncolytic bacteria HCS1 exerts high immune stimulation and safety profiles for cancer therapy https://doi.org/10.7150/thno.87340 Enteric glial cells aggravate the intestinal epithelial barrier damage by secreting S100beta under high-altitude conditions https://doi.org/10.1186/s43556-023-00143-1 Evaluation of time-dependent phenotypes of myocardial ischemia-reperfusion in mice https://doi.org/10.18632/aging.205103 GAS1 Promotes Ferroptosis of Liver Cells in Acetaminophen-Induced Acute Liver Failure https://doi.org/10.7150/ijms.85114 HBV suppresses macrophage immune responses by impairing the TCA cycle through the induction of CS/PDHC hyperacetylation https://doi.org/10.1097/HC9.0000000000000294 Icaritin ameliorates RANKL-mediated osteoclastogenesis and ovariectomy-induced osteoporosis https://doi.org/10.18632/aging.205068 Identification of novel SCD1 inhibitor alleviates nonalcoholic fatty liver disease: critical role of liver-adipose axis https://doi.org/10.1186/s12964-023-01297-9 IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma https://doi.org/10.1038/s41467-023-42545-3 Insights into the Mechanism of Supramolecular Self-Assembly in the Astragalus membranaceus-Angelica sinensis Codecoction https://doi.org/10.1021/acsami.3c09494 Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity https://doi.org/10.1016/j.celrep.2023.113211 Lithium chloride induces apoptosis by activating endoplasmic reticulum stress in pancreatic cancer https://doi.org/10.1016/j.tranon.2023.101792 Metformin potentiates nephrotoxicity by promoting NETosis in response to renal ferroptosis https://doi.org/10.1038/s41421-023-00595-3 MUC1 attenuates neutrophilic airway inflammation in asthma by reducing NLRP3 inflammasome-mediated pyroptosis through the inhibition of the TLR4/MyD88/NF-kappaB pathway https://doi.org/10.1186/s12931-023-02550-y Novel cannabinoid receptor 1 inverse agonist CRB-913 enhances efficacy of tirzepatide, semaglutide, and liraglutidein the diet-induced obesity mouse model https://doi.org/10.1002/oby.23902 Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine https://doi.org/10.1016/j.xcrm.2023.101229 Oxymatrine inhibits melanoma development by modulating the immune microenvironment and targeting the MYC/PD-L1 pathway https://doi.org/10.1016/j.intimp.2023.111000 PUFAs add fuel to Crohn's disease-associated AIEC-induced enteritis by exacerbating intestinal epithelial lipid peroxidation https://doi.org/10.1080/19490976.2023.2265578 Pyrroline-5-carboxylate reductase 1 reprograms proline metabolism to drive breast cancer stemness under psychological stress https://doi.org/10.1038/s41419-023-06200-5 Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease https://doi.org/10.1016/j.cmet.2022.10.002 MircroRNA-92b as a negative regulator of the TGF-beta signaling by targeting the type I receptor https://doi.org/10.1016/j.isci.2023.108131 Defects in a liver-bone axis contribute to hepatic osteodystrophy disease progression https://pubmed.ncbi.nlm.nih.gov/35235775/ Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis https://doi.org/10.1016/j.ejphar.2022.175241 Excessive iron inhibits insulin secretion via perturbing transcriptional regulation of SYT7 by OGG1 https://doi.org/10.1007/s00018-023-04802-y A single-cell transcriptomic atlas characterizes age-related changes of murine cranial stem cell niches https://doi.org/10.1111/acel.13980 Aloperine targets lysosomes to inhibit late autophagy and induces cell death through apoptosis and paraptosis in glioblastoma https://doi.org/10.1186/s43556-023-00155-x Aortic calcification accelerates cardiac dysfunction via inducing apoptosis of cardiomyocytes https://doi.org/10.7150/ijms.90324 Blockage of CacyBP inhibits macrophage recruitment and improves anti-PD-1 therapy in hepatocellular carcinoma https://doi.org/10.1186/s13046-023-02885-w Costal Cartilage Graft Repair Osteochondral Defect in a Mouse Model https://doi.org/10.1177/19476035231209404 Discovery of Zidovudine as a cardiomyocyte protectant for doxorubicin-induced toxicity through high-throughput phenotypic drug screening https://doi.org/10.1016/j.fmre.2023.10.010 Does decreased autophagy and dysregulation of LC3A in astrocytes play a role in major depressive disorder? https://doi.org/10.1038/s41398-023-02665-2 Group 3 Innate Lymphoid Cells Exacerbate Lupus Nephritis by Promoting B Cell Activation in Kidney Ectopic Lymphoid Structures https://doi.org/10.1002/advs.202302804 Highly efficient conversion of mouse fibroblasts into functional hepatic cells under chemical induction https://doi.org/10.1093/jmcb/mjad071 Hollow Cu2MoS4 nanoparticles loaded with immune checkpoint inhibitors reshape the tumor microenvironment to enhance immunotherapy for pancreatic cancer https://doi.org/10.1016/j.actbio.2023.10.024 Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect https://doi.org/10.1128/jvi.00796-23 Interferon stimulated immune profile changes in a humanized mouse model of HBV infection https://doi.org/10.1038/s41467-023-43078-5 Liposome-Based Silibinin for Mitigating Nonalcoholic Fatty Liver Disease: Dual Effects via Parenteral and Intestinal Routes https://doi.org/10.1021/acsptsci.3c00210 Metabolomics study reveals increased deoxycholic acid contributes to deoxynivalenol-mediated intestinal barrier injury https://doi.org/10.1016/j.lfs.2023.122302 Mirabegron displays anticancer effects by globally browning adipose tissues https://doi.org/10.1038/s41467-023-43350-8 PKM2 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Induces Phenotype Switching of Cancer-Associated Fibroblasts to Tumor Suppressive in Prostate Cancer https://doi.org/10.1158/0008-5472.CAN-24-0932/3484967/can-24-0932.pdf DAP3 promotes mitochondrial activity and tumour progression in hepatocellular carcinoma by regulating MT-ND5 expression https://doi.org/10.1038/s41419-024-06912-2 Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC https://doi.org/10.1016/j.jare.2024.08.021 Targeting tumor-associated macrophage-derived CD74 improves efficacy of neoadjuvant chemotherapy in combination with PD-1 blockade for cervical cancer https://doi.org/10.1136/jitc-2024-009024 Dysbiosis promotes recurrence of adenomatous polyps in the distal colorectum https://doi.org/10.4251/wjgo.v16.i8.3600 Crystalline silica-induced recruitment and immuno-imbalance of CD4(+) tissue resident memory T cells promote silicosis progression https://doi.org/10.1038/s42003-024-06662-z Zdhhc1- and 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translocation of mitochondrial ACSL1 impairs adipocyte thermogenesis and energy expenditure in male mice https://doi.org/10.1038/s41467-024-52218-4 EXTL3 and NPC1 are mammalian host factors for Autographa californica multiple nucleopolyhedrovirus infection https://doi.org/10.1038/s41467-024-52193-w Local administration of mRNA encoding cytokine cocktail confers potent anti-tumor immunity https://doi.org/10.3389/fimmu.2024.1455019 Targeting IL-33 reprograms the tumor microenvironment and potentiates antitumor response to anti-PD-L1 immunotherapy https://doi.org/10.1136/jitc-2024-009236 METTL16-SENP3-LTF axis confers ferroptosis resistance and facilitates tumorigenesis in hepatocellular carcinoma https://doi.org/10.1186/s13045-024-01599-6 Meis1 Targets Protein Tyrosine Phosphatase Receptor J in Fibroblast to Retard Chronic Kidney Disease Progression https://doi.org/10.1002/advs.202309754 ACSL6-activated IL-18R1–NF-κB promotes IL-18–mediated tumor immune evasion and tumor progression. https://doi.org/10.1126/sciadv.adp071 Enhanced tumor targeting and penetration of fluorophores via iRGD peptide conjugation: a strategy for the precision targeting of lung cancer https://doi.org/10.21037/tlcr-24-589
*使用本品系发表的文献需注明：C57BL/6JGpt mice（Strain NO.N000013）were purchased from GemPharmatech (Nanjing, China).
